3,3-Diethyl-2-pyrrolidinone
Chemical compound
- none
- 3,3-Diethylpyrrolidin-2-one
- 175698-05-2 N
- 9793807
- 7969574 Y
- YW6BG9J9SK
- CHEBI:180486
- ChEMBL293075 Y
- DTXSID60430723
- Interactive image
- CCC1(CC)CCNC1=O
InChI
- InChI=1S/C8H15NO/c1-3-8(4-2)5-6-9-7(8)10/h3-6H2,1-2H3,(H,9,10) Y
- Key:WYPUMACPRYGQOM-UHFFFAOYSA-N Y
3,3-Diethyl-2-pyrrolidinone (DEABL) is an anticonvulsant drug most closely related to pyrithyldione and gabapentin.[1] It was found to extend lifespan in the nematode worms Caenorhabditis elegans.[2]
References
- ^ Hill MW, Reddy PA, Covey DF, Rothman SM (July 1998). "Contribution of subsaturating GABA concentrations to IPSCs in cultured hippocampal neurons". The Journal of Neuroscience. 18 (14): 5103–11. doi:10.1523/JNEUROSCI.18-14-05103.1998. PMC 6793480. PMID 9651194.
- ^ Evason K, Huang C, Yamben I, Covey DF, Kornfeld K (January 2005). "Anticonvulsant medications extend worm life-span". Science. 307 (5707): 258–62. Bibcode:2005Sci...307..258E. doi:10.1126/science.1105299. PMID 15653505. S2CID 22154410.
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Anticonvulsants (N03)
modulators
CA inhibitors |
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Others |
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
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