FUNDC1

Protein-coding gene in humans
FUNDC1
Identifiers
AliasesFUNDC1, FUN14 domain containing 1
External IDsOMIM: 300871; MGI: 1919268; HomoloGene: 41738; GeneCards: FUNDC1; OMA:FUNDC1 - orthologs
Gene location (Human)
X chromosome (human)
Chr.X chromosome (human)[1]
X chromosome (human)
Genomic location for FUNDC1
Genomic location for FUNDC1
BandXp11.3Start44,523,639 bp[1]
End44,542,859 bp[1]
Gene location (Mouse)
X chromosome (mouse)
Chr.X chromosome (mouse)[2]
X chromosome (mouse)
Genomic location for FUNDC1
Genomic location for FUNDC1
BandX|X A1.2Start17,422,803 bp[2]
End17,438,564 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • myocardium of left ventricle

  • pons

  • lateral nuclear group of thalamus

  • palpebral conjunctiva

  • cardiac muscle tissue of right atrium

  • oocyte

  • hypothalamus

  • cingulate gyrus

  • anterior cingulate cortex

  • nucleus accumbens
Top expressed in
  • facial motor nucleus

  • anterior horn of spinal cord

  • sciatic nerve

  • substantia nigra

  • trigeminal ganglion

  • olfactory epithelium

  • interventricular septum

  • medial vestibular nucleus

  • medial ganglionic eminence

  • median eminence
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • protein binding
Cellular component
  • integral component of membrane
  • integral component of mitochondrial outer membrane
  • membrane
  • mitochondrion
  • mitochondrial outer membrane
Biological process
  • autophagy
  • response to hypoxia
  • autophagy of mitochondrion
  • response to organonitrogen compound
  • macroautophagy
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

139341

72018

Ensembl

ENSG00000069509

ENSMUSG00000025040

UniProt

Q8IVP5

Q9DB70

RefSeq (mRNA)

NM_173794

NM_028058
NM_001313745
NM_001313746

RefSeq (protein)

NP_776155

NP_001300674
NP_001300675
NP_082334

Location (UCSC)Chr X: 44.52 – 44.54 MbChr X: 17.42 – 17.44 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

FUN14 domain containing 1 is a protein that in humans is encoded by the FUNDC1 gene.[5]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000069509 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000025040 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: FUN14 domain containing 1". Retrieved 2011-09-19.

Further reading

Terracciano A, Sanna S, Uda M, Deiana B, Usala G, Busonero F, et al. (June 2010). "Genome-wide association scan for five major dimensions of personality". Molecular Psychiatry. 15 (6): 647–656. doi:10.1038/mp.2008.113. PMC 2874623. PMID 18957941.

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