Fluperolone acetate

Chemical compound
  • D07AB05 (WHO)
Identifiers
  • (2S)-1-[(1R,2S,10S,11S,14R,15S,17S)-1-fluoro-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0.02,7.011,15]heptadeca-3,6-dien-14-yl]-1-oxopropan-2-yl acetate
CAS Number
  • 2119-75-7 checkY
PubChem CID
  • 66257
ChemSpider
  • 59639
UNII
  • DOL7Q9DPF9
KEGG
  • D04225
CompTox Dashboard (EPA)
  • DTXSID50895064 Edit this at Wikidata
ECHA InfoCard100.016.662 Edit this at WikidataChemical and physical dataFormulaC24H31FO6Molar mass434.504 g·mol−13D model (JSmol)
  • Interactive image
  • C[C@@H](C(=O)[C@]1(CC[C@@H]2[C@@]1(C[C@@H]([C@]3([C@H]2CCC4=CC(=O)C=C[C@@]43C)F)O)C)O)OC(=O)C
InChI
  • InChI=1S/C24H31FO6/c1-13(31-14(2)26)20(29)23(30)10-8-17-18-6-5-15-11-16(27)7-9-21(15,3)24(18,25)19(28)12-22(17,23)4/h7,9,11,13,17-19,28,30H,5-6,8,10,12H2,1-4H3/t13-,17-,18-,19-,21-,22-,23-,24-/m0/s1
  • Key:HHPZZKDXAFJLOH-QZIXMDIESA-N
  (verify)

Fluperolone acetate is a corticosteroid. It has been used topically.[1]

References

  1. ^ Thorne N (March 1963). "A clinical trial of Fluperolone, a new topical steroid". Postgraduate Medical Journal. 39 (449): 159–60. doi:10.1136/pgmj.39.449.159. PMC 2482046. PMID 13984971.
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Glucocorticoids and antiglucocorticoids (D07, H02)
Glucocorticoids
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Glucocorticoid receptor modulators
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List of corticosteroids
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GRTooltip Glucocorticoid receptor
Agonists
  • Nonsteroidal glucocorticoids: AZD-5423
  • GSK-9027
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Antagonists
Others
  • Antisense oligonucleotides: IONIS-GCCRRx (ISIS-426115)
See also
Receptor/signaling modulators
Glucocorticoids and antiglucocorticoids
Mineralocorticoid receptor modulators
List of corticosteroids
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