Epoksidna hidrolaza
| Epoksidna hidrolaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 | |||||||||
| Epoksidna hidrolaza 2, dimer, Human | |||||||||
| Identifikatori | |||||||||
| EC broj | 3.3.2.3 | ||||||||
| CAS broj | 9048-63-9 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Epoksidna hidrolaza (EC 3.3.2.3, epoksidna hidrataza, aren-oksidna hidrataza, benzo(a)piren-4,5-oksidna hidrataza, benzo(a)piren-4,5-epoksidna hidrataza, aril epoksidna hidraza, cis-epoksidna hidrolaza, trans-stilbensko oksidna hidrolaza, ksenobiotsko epoksidna hidrolaza) je enzim sa sistematskim imenom epoksidna hidrolaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- epoksid + H2O glikol
Ovaj enzim deluje na mnoštvo epoksidnih i arenskih oksida.
Reference
- ↑ Jakoby, W.B. and Fjellstedt, T.A. (1972). „Epoxidases”. u: Boyer, P.D.. The Enzymes. 7 (3rd izd.). New York: Academic Press. str. 199-212.
- ↑ Lu, A.Y.H., Ryan, D., Jerina, D.M., Daly, J.W. and Levin, W. (1975). „Liver microsomal epoxide hydrase. Solubilization, purification, and characterization”. J. Biol. Chem. 250: 8283-8288.
- ↑ Oesch, F. (1974). „Purification and specificity of a human microsomal epoxide hydratase”. Biochem. J. 139: 77-88. PMID 4463951.
- ↑ Oesch, F. and Daly, J. (1971). „Solubilization, purification, and properties of a hepatic epoxide hydrase”. Biochim. Biophys. Acta 227: 692-697. PMID 4998715.
Literatura
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.
- Jakoby, W.B. and Fjellstedt, T.A. (1972). „Epoxidases”. u: Boyer, P.D.. The Enzymes. 7 (3rd izd.). New York: Academic Press. str. 199-212.
Spoljašnje veze
- MeSH Epoxide+hydrolase
- p
- r
- u
Aktivno mesto • Alosterna regulacija • Mesto vezivanja • Katalitički perfektan enzim • Koenzim • Kofaktor • Kooperativnost • EC broj • Enzimska kataliza • Inhibicija enzima • Enzimska kinetika • Lajnviver–Burk dijagram • Mihaelis–Mentenova kinetika • Spisak enzima
EC1 Oksidoreduktaze/spisak • EC2 Transferaze/spisak • EC3 Hidrolaze/spisak • EC4 Lijaze/spisak • EC5 Izomeraze/spisak • EC6 Ligaze/spisak
B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6
