Ferohelataza

Ferohelataza
Identifikatori
EC broj4.99.1.1
CAS broj9012-93-5
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IntEnzIntEnz pregled
BRENDABRENDA pristup
ExPASyNiceZyme pregled
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Strukture PBPRCSB PDB PDBe PDBj PDBsum
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NCBIproteini

Ferohelataza (EC 4.99.1.1, fero-protoporfirin helataza, gvožđe helataza, hem sintetaza, hem sintaza, protoheme fero-lijaza) je enzim sa sistematskim imenom protohem fero-lijaza (formira protoporfirin).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju

protohem + 2 H+ {\displaystyle \rightleftharpoons } protoporfirin + Fe2+

Reference

  1. ^ Bloomer, J.R., Hill, H.D., Morton, K.O., Anderson-Burnham, L.A. and Straka, J.G. (1987). „The enzyme defect in bovine protoporphyria. Studies with purified ferrochelatase”. J. Biol. Chem. 262: 667—671. PMID 3805002. CS1 одржавање: Вишеструка имена: списак аутора (веза)
  2. ^ Porra, R.J. & Jones, O.T. (1963). „Studies on ferrochelatase. 1. Assay and properties of ferrochelatase from a pig-liver mitochondrial extract”. Biochem. J. 87: 181—185. PMID 13972328. 
  3. ^ Porra, R.J. & Jones, O.T. (1963). „Studies on ferrochelatase. 2. An investigation of the role of ferrochelatase in the biosynthesis of various haem prosthetic groups”. Biochem. J. 87: 186—192. PMID 13972329. 

Literatura

  • Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X. 
  • Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036. 
  • Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0. 
  • Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097. 
  • William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605. 

Spoljašnje veze

  • Ferrochelatase на US National Library of Medicine Medical Subject Headings (MeSH)
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TemeTipovi
  • B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6
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