Tiazid
Tiazid je tip molekula[1] i klasa diuretika[2] koji se često koriste za tretiranje hipertenzije (visokog krvnog pristiska) i edema (poput onih uzrokovanih bolestima srca, jetre, ili bubrega).
Tiazidi i tiazidima slični diuretici redukuju rizik od smrti, šloga, srčanog udara i zatajenja srca usled hipertenzije.[3] U većini zemalja, tiazidi su najjeftiniji antihipertenzivni lekovi.[4]
Reference
- ^ Thiazides на US National Library of Medicine Medical Subject Headings (MeSH)
- ^ Thiazide+Diuretics на US National Library of Medicine Medical Subject Headings (MeSH)
- ^ Wright JM, Musini VM (2009). Wright JM, ур. „First-line drugs for hypertension”. Cochrane Database Syst Rev. 8 (3): CD001841. PMID 19588327. doi:10.1002/14651858.CD001841.pub2.
- ^ Whitworth, JA (2003). World Health Organization, International Society of Hypertension Writing Group. „2003 World Health Organization (WHO)/International Society of Hypertension (ISH) statement on management of hypertension”. J Hypertens. 21 (11): 1983—92. PMID 14597836. doi:10.1097/00004872-200311000-00002.
Literatura
- Bertram G. Katzung: Basic and Clinical Pharmacology. Kapitel 15 Diuretic agents. Mcgraw-Hill Professional. 9th Edition. 2004. ISBN 978-0-07-141092-2.
- Donald W. Seldin (Hrsgb.), Gerhard Giebisch (Hrsgb.): Diuretic Agents: Clinical Physiology and Pharmacology. Kapitel 3 A history of diuretics, S. 3 ff. und Kapitel Academic Press. 1st edition. 1997. ISBN 978-0-12-635690-8.
- Craig, Stitzel: Modern Pharmacology with Clinical Applications. Kapitel 21 Diuretic Drugs, S. 249 ff. Lippincott Raven, 6th Edition. 2003. ISBN 978-0-7817-3762-3.
Spoljašnje veze
- Thiazide diuretics
- p
- r
- u
Antihipertenzivi: diuretici (C03)
(izuzev EK)
| KA inhibitor (u PT) | |
|---|---|
| Henleova Petlja (Na-K-Cl u AL) | |
| Tiazidi (Na-Cl u DCT, Kalcijum-oskudni) | |
| Tiazid-slični (prvenstveno DCT) | Kinetazon • Klopamid • Hlortalidon • Mefrusid • Klofenamid • Metolazon • Metikran • Ksipamid • Indapamid • Kloreksolon • Fenkizon |
| ESC blokeri | |
|---|---|
| Antimineralokortikoid |
| |||||
Нормативна контрола  |
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